
Vivostat Autologous Fibrin
Vivostat® Fibrin Sealant is an autologous fibrin that helps minimize CSF leakages. Furthermore, it acts as a “filler” in “dead space” thereby minimizing the risk of infections. Vivostat® Fibrin Sealant has excellent bio-physical properties. Comparative tests stress the superior elasticity and adhesion of Vivostat® Fibrin Sealant and the autologous nature of Vivostat® efficiently eliminates the risk of bovine or human borne contaminants. Unlike most other fibrin sealants no thrombin is added to Vivostat® Fibrin Sealant. This is beneficiary as it has been shown that thrombin may have a negative effect on cell proliferation.
Dr. Peter Siesjà¸, Division of Neurosurgery, Lund University Hospital, Sweden explains the effect of Vivostat® Fibrin Sealant: “At Lund University Hospital we have been able to reduce the incidence of CSF leakages substantially by using Vivostat® Fibrin Sealant, further, we have been able to reduce the frequency of infections”.
Vivostat® Fibrin Sealant can be used for a number of different procedures.
- Dural closure
- Repair of dural defects
- Spinal fusions
- Tumor resections
- Filler in “dead spaces”
The unique Vivostat® application technology ensures that Vivostat® Fibrin Sealant polymerizes immediately upon application. Furthermore, it offers the surgeon different spray modes, e.g. “No Air” that allows application with low impact on tissue and vital organs/nerves in the skull. A comparative study supports the low impact on the tissue and further stresses that Vivostat® can be applied with extreme accuracy.
Vivostat® Fibrin Sealant can be used intermittently throughout the entire procedure without experiencing the blockage that is common in conventional fibrin sealant systems and it is possible to perform applications endoscopically.

